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Squamous Cell Carcinoma of the Buccal MucosaA Review of 85 Cases
Johannes W. M. Vegers, MD;
Gordon B. Snow, MD;
Isaac van der Waal, DDS
Arch Otolaryngol. 1979;105(4):192-195.
Abstract
• Of 85 cases of squamous cell carcinoma of the buccal mucosa, 61 were treated primarily and 24 secondarily. Sixty-one percent (39) were T3 lesions, and 59% (38) had regional metastases. Nearly half of the patients were more than 70 years of age. Thirty-one percent (19) of the primary patients were treated by surgery alone, 25% (15) by irradiation alone, and 36% (22) by various combinations. The absolute five-year cure rate was 45% for the whole group, and 54% for the primarily and 40% for the secondarily treated patients. For each individual T and N category, the results of surgery were superior over those of radiotherapy. Intra-arterial chemotherapy followed by radiotherapy is to be considered in advanced cases, where composite resection on general grounds is not contemplated. There was a 14% incidence of second primary cancers; these were mainly located in the oral cavity.
(Arch Otolaryngol 105:192-195, 1979)
Author Affiliations
From the Department of Otorhinolaryngology, Free University Hospital and the Department of Head and Neck Surgery, Netherlands Cancer Institute, Amsterdam.
Footnotes
Accepted for publication Sept 7, 1978.
Read before the combined meeting of the Society of Head and Neck Surgery and the American Society of Head and Neck Surgeons, Toronto, May 29, 1978.
Reprint requests to Department of Otorhinolaryngology, Free University Hospital, De Boelelaan 1117 at 1007 MB Amsterdam, Netherlands (Dr Snow).
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