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Privileged Tissue or Privileged Site

Normand B. Gagnon, MD; Jacques Piche, MD; Daniel Larochelle, MD; Malcolm L. Williams, MD

Arch Otolaryngol. 1979;105(1):35-38.

Abstract
• To explain the survival and behavior of homografts, we have tried, by means of discussion and use of biological models, to resolve a problem with three unknowns, ie, the tympanic membrane, the ossicle, and the middle ear, with the notions of privileged tissue and privileged site. The tympanic membrane survives because of the relative stability of its fibers and the absence of mechanical trauma. Later, the membrane is sheathed by fibrous tissue. The ossicle is not only tolerated by the host but is also invaded and ossified.

(Arch Otolaryngol 105:35-38, 1979)

Author Affiliations
From the Ear, Nose, and Throat Division, Department of Surgery, University of Montreal (Drs Gagnon, Piche, and Larochelle), and the Department of Otolaryngology, Queen's University, Kingston, Ontario (Dr Williams).

Footnotes
Accepted for publication June 18, 1978.

Reprint requests to Ear, Nose and Throat Division, Department of Surgery, University of Montreal, 822 Sherbrooke St E, Montreal, Quebec, Canada (Dr Gagnon).

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