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Lethal Thyroid Carcinoma
Horst R. Konrad, MD;
Rinaldo F. Canalis, MD
Arch Otolaryngol. 1978;104(8):454-455.
Abstract
Forty-three patients who died of thyroid carcinoma (29 well-differentiated and 14 poorly differentiated tumors) were evaluated to define the parameters that affect the lethal nature of this tumor. Differentiated, limited extent of tumor and a young age at diagnosis correlated favorably with length of survival. Sex showed a trend in favor of female patients, while specific histologic characteristics and extent of resection showed no positive correlation. Based on these findings and a review of the literature, we recommend a radical approach in the management of localized, poorly differentiated tumors. For well-differentiated cancer, resection of the thyroid gland and the paratracheal, jugular, and upper mediastinal lymph nodes is advised.
(Arch Otolaryngol 104:454-455, 1978)
Author Affiliations
From the Head and Neck Division, Department of Surgery, The Center for the Health Sciences, UCLA School of Medicine, Los Angeles. Dr Konrad is now with the Division of Otolaryngology, Southern Illinois University School of Medicine, Springfield.
Footnotes
Accepted for publication March 16, 1978.
Reprint requests to Division of Otolaryngology, Southern Illinois University School of Medicine, 200 W Dodge St, Springfield, IL 62708 (Dr Konrad).
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