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Robert J. Brown, MD; Norbert J. Szymula, MD; John M. Loré, Jr, MD

Arch Otolaryngol. 1978;104(7):395-398.

Abstract
• We reviewed 105 cases of neuroblastoma, which were seen at the Buffalo Children's Hospital between 1936 and 1976. We describe seven patients with primary neuroblastoma of the head and neck. The results of postmortem examination in two of these patients proved without any doubt that the tumor was primarily in the head and neck region.

Although metastasis of neuroblastomas to the head and neck from more common primary sites in the abdomen, pelvis, or thorax is common, to our knowledge, well-documented primary head and neck lesions are quite rare.

The prognosis of invasive neuroblastoma of the head and neck is poor, with rapid and widespread metastasis being the rule. However, some success has been reported with early and massive therapy that involves surgery, chemotherapy, and radiation therapy.

(Arch Otolaryngol 104:395-398, 1978)

Author Affiliations
From the House of the Good Samaritan Hospital and Mercy Hospital, Watertown, NY (Dr Brown), and the Department of Otolaryngology, School of Medicine, State University of New York, Buffalo (Drs Szymula and Lore).

Footnotes
Accepted for publication Dec 13, 1977.

Reprint requests to Department of Otolaryngology, State University of New York, Seton Professional Bldg, 2121 Main St, Suite 208, Buffalo, NY 14214 (Dr Lore).

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ABSTRACT