 |
|
Impedance Audiometry in the Squirrel MonkeySensorineural Losses
James Jerger, PhD;
Larry Mauldin;
Makoto Igarashi, MD
Arch Otolaryngol. 1978;104(10):559-563.
Abstract
• Acoustic reflex thresholds for pure tones and broad-band noise were measured before and after treatment of nine squirrel monkeys. Experimental sensorineural hearing loss was created in six monkeys by ototoxic drug administration (gentamicin) and in three monkeys by exposure to intense sound. Extent of cochlear damage was assessed histopathologically, in the case of permanent loss induced by the ototoxic agent, and inferred from exposure history, in the case of the reversible loss induced by exposure to intense sound. Posttreatment changes in relationships among acoustic reflex thresholds (noise-tone difference [NTD]) reflected approximate degree of cochlear damage. Serial measurement of changes in the NTD in acoustic reflex thresholds appears to be a worthwhile and useful technique for monitoring sensorineural levels in the squirrel monkey.
(Arch Otolaryngol 104:559-563, 1978)
Author Affiliations
From the Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, and the Neurosensory Center, Houston.
Footnotes
Accepted for publication Jan 28, 1978.
Reprint requests to Division of Audiology and Speech Pathology, Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, 1200 Moursund Ave, Houston, TX 77030 (Dr Jerger).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Effect of Ketamine on the Stapedius Reflex in the Squirrel Monkey
Thompson et al.
Arch Otolaryngol Head Neck Surg 1984;110:22-24.
ABSTRACT
Impedance Audiometry in the Squirrel Monkey: Effect of Transection of Crossed Olivocochlear Bundle
Igarashi et al.
Arch Otolaryngol Head Neck Surg 1979;105:258-259.
ABSTRACT
|
