This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Karl L. Horn, MD; Lynn R. Langley, MA; George A. Gates, MD

Arch Otolaryngol. 1977;103(9):539-541.

Abstract
• The stria vascularis of young albino guinea pigs was examined by scanning electron microscopy at intervals of 30, 60, and 240 minutes after the intracardiac administration of ethacrynic acid (70 mg/kg). Results from this study showed that the appearance of large intercellular spaces in the intermediate region of the stria vascularis was due to acute separation of these cells rather than atrophy, as described by previous investigators. It was probable that these spaces were due to an accumulation of extracellular fluid. In some marginal cells, extrusions of cytoplasm into the endolymphatic space were noted in the 240-minute group of animals. The importance of these extrusions is not apparent at this time.

(Arch Otolaryngol 103:539-541, 1977)

Author Affiliations
From the Departments of Otolaryngology (Drs Horn and Gates and Ms Langley) and Anatomy (Dr Horn), University of Texas Health Science Center, San Antonio. Dr Horn is now with the Department of Otolaryngology, University of California, San Francisco.

Footnotes
Accepted for publication Feb 25, 1977.

Reprint requests to Department of Otolaryngology, University of California, San Francisco, CA 94143 (Dr Horn).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Comparative Ototoxicity of Chloramphenicol and Kanamycin With Ethacrynic Acid
Beaugard et al.
Arch Otolaryngol Head Neck Surg 1981;107:104-109.
ABSTRACT