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Part of a Cranial Polyneuropathy?

Gisle Djupesland, MD; Miklos Degré, MD; Ragnar Stien, MD; Sverre Skrede, MD

Arch Otolaryngol. 1977;103(11):641-644.

Abstract
• In 14 of 16 consecutive patients with acute peripheral facial palsy, one or more (up to four) other nerves were involved. The nerves affected in addition to the facial nerve were as follows: trigeminal (ten patients), vestibular (eight), cochlear (six), vagus (one), and upper cervical (five).

Virus was not isolated from any of the patients. A fourfold increase or decrease in complement-fixing antibody titers was present in eight patients (in four, varicella-zoster; in one, varicella-zoster and mumps; in two, cytomegalovirus; in one, mumps). Further, two of the patients with varicella-zoster antibodies showed clinical signs of herpes zoster oticus. About one fourth of all patients had an increase of ESR and of ₂-globulins in serum, and two thirds of them had increased -globulins in CSF. Acute peripheral facial palsy seems to be part of a cranial polyneuropathy and may be caused by a viral infection.

(Arch Otolaryngol 103:641-644, 1977)

Author Affiliations
From the Departments of Otolaryngology (Dr Djupesland), Bacteriology (Dr Degré), Neurology (Dr Stien), and Clinical Chemistry (Dr Skrede), Rikshospitalet, National Hospital of Norway, University Hospital, Oslo.

Footnotes
Accepted for publication April 5, 1977.

Reprint requests to Department of Otolaryngology, Rikshospitalet, National Hospital of Norway, University Hospital, Oslo, Norway (Dr Djupesland).

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