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Tauno Palva, MD; Pekka Karma, MD; Antti Palva, MD

Arch Otolaryngol. 1976;102(5):271-275.

Abstract
• Mucosal biopsy specimens were taken from the middle ear in 19 patients with otosclerosis and stained by Alcian blue and PAS. They were also stained for hydrolytic and oxidative enzymes. In addition, 11 temporal bones from patients without any previous ear disease were serially sectioned for mucopolysaccharides. In otosclerosis, both acid and neutral mucopolysaccharides were present in the mucosa, but not to the same extent as in the temporal bone specimens. Acid phosphatase, lactate malate dehydrogenases, and nonspecific esterase were demonstrated even in very thin epithelium, providing a potential basis for the appearance of these enzymes in large amounts in various inflammatory middle ear diseases.

(Arch Otolaryngol 102:271-275, 1976)

Author Affiliations
From the Department of Otolaryngology, University of Helsinki (Dr T. Palva), and the Department of Otolaryngology, University of Oulu, (Drs Karma and A. Palva) Finland.

Footnotes
Accepted for publication Jan 13, 1976.

Reprint requests to the Department of Otolaryngology, University of Helsinki, Haartmanikatu 4 E, Helsinki 29, Finland (Dr T. Palva).

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