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Dale H. Rice, MD; Gus Gill, MD

Arch Otolaryngol. 1976;102(2):99-100.

Abstract
• A substantial number of patients with intraoral malignant neoplasms have abnormal bacterial flora of skin, nasopharynx, and oropharynx, without a demonstrable relationship between tumor size, location, or degree of ulceration.¹ Seventeen consecutive patients were studied to determine what relationship, if any, exists between the presence of abnormal microorganisms and the patients' immunological competence. Ten of 17 patients grew potentially pathogenic organisms, and all reacted to specific skin tests used to infer immunological competence. Thus, there appeared to be no relationship between cellular immunity and the presence of abnormal bacteria in patients with intraoral malignant neoplasms.

(Arch Otolaryngol 102:99-100, 1976)

Author Affiliations
From the Department of Otorhinolaryngology, University of Michigan Medical Center, Ann Arbor.

Footnotes
Accepted for publication Oct 6, 1975.

Reprint requests to the Department of Otorhinolaryngology, University Hospital, University of Michigan Medical Center, Ann Arbor, MI 48104 (Dr Rice).

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