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Is the Vidian Nerve Cholinergic?
Robert Gadlage, MD;
Ernest E. Behnke, MD;
Richard T. Jackson, PhD
Arch Otolaryngol. 1975;101(7):422-425.
Abstract
Electrical stimulation of the parasympathetic nerve (vidian) to the nasal mucosa induces a nasal secretion and a nasal vasodilation. We have provided additional evidence that, in the dog and cat, the secretory mechanism can be blocked with low doses of atropine sulfate (0.01 mg/kg), but the dilation mechanism is not blocked by high doses (1 mg/kg, of atropine sulfate.
By some definitions therefore, the vasodilation is not a cholinergic effect. There appears to be a basic difference in the composition of the vidian nerve in the dog and cat. In the cat, the vidian appears to have a strong sympathetic component. In the dog it does not. The human vidian nerve, according to anatomists, is more like the dog's.
Author Affiliations
From the Division of Otolaryngology, Emory University School of Medicine, Atlanta.
Footnotes
Accepted for publication Feb 25, 1975.
Reprint requests to 441 Woodruff Memorial Bldg, Emory University, Atlanta, GA 30322 (Dr. Jackson).
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