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  Vol. 101 No. 5, May 1975 TABLE OF CONTENTS
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Electrolytic Lesioning in the Cochlea

John A. Ferraro, PhD; Peter Dallos, PhD

Arch Otolaryngol. 1975;101(5):312-315.


Abstract

A method has been developed whereby relatively discrete portions of the organ of Corti can be selectively destroyed with the use of a high-frequency current. The procedure involves passing the current (1 to 3 ma at an approximate frequency of 5 megahertz) between a differential pair of recording electrodes located in the scalae vestibuli and tympani of a particular cochlear turn.

Damage patterns progressing from partial to complete outer hair cell lesioning and eventually to the inner hair cells accompanied by progressive decreases in cochlear microphonic sensitivity can be effected.



Author Affiliations

From the Auditory Research Laboratory, and the Department of Electrical Engineering, Northwestern University, Evanston, Ill. Dr. Ferraro is currently with the Speech and Hearing Science Division, Department of Communication, Ohio State University, Columbus.


Footnotes

Accepted for publication Sept 20, 1974.

Reprint requests to the Speech and Hearing Science Section, Department of Communication, Ohio State University, Columbus, OH 43210 (Dr. Ferraro).



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