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Surface-Active Agent in Eustachian Tube Function
Philip N. Rapport;
David J. Lim, MD;
Harold S. Weiss, PhD
Arch Otolaryngol. 1975;101(5):305-311.
Abstract
Using 15 fresh guinea pig temporal bones, Eustachian tubal function was tested repeatedly before and after saline washing to demonstrate the effect of surface-active agent. Although tubal opening pressures for the 15 ears varied considerably, in each ear tested, a higher pressure was required to open the Eustachian tube after saline washing (P <.001).
A significant statistical difference in Eustachian tube opening pressure was also found between consecutive trials before washing the Eustachian tube with saline (P <.001). This phenomenon disappeared after saline washing. It is possible that these phenomena occurred as a result of surface-active agent (surfactant) functioning in the Eustachian tube.
Author Affiliations
From the Otological Research Laboratory, Department of Otolaryngology (Dr. Lim and Mr. Rapport); and the Department of Physiology (Dr. Weiss), Ohio State University College of Medicine, Columbus.
Footnotes
Accepted for publication Sept 20, 1974.
Reprint requests to the Otological Research Laboratory, the Ohio State University Hospitals, 456 Clinic Dr, Columbus, OH 43210 (Dr. Lim).
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