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A Ten-Year Follow-Up

James F. Smith, DDS, PhD, MD

Arch Otolaryngol. 1975;101(5):276-277.

Abstract
A population of over 15,000 snuff users and tobacco chewers were observed for cytological, histological, and clinical evaluation. The original observation was for 5 years. The same group was observed for an additional 4 years, bringing the total time to ten years. Of the original group of 1,751 patients showing mucosal change, I was able to follow up 1,550. No patient developed carcinoma or serious mucosal changes. From this ten-year study we concluded that snuff, per se, or chewing tobacco do not act as carcinogens.

Author Affiliations
From the Department of Otolaryngology, University of Tennessee College of Medicine, Memphis.

Footnotes
Accepted for publication Dec 5, 1974.

Reprint requests to the Department of Otolaryngology, University of Tennessee College of Medicine, 858 Madison-827, Memphis, TN 38103 (Dr. Smith).

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